Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15460780 | 0.91 | S1PR1 (0.34) | S1PR1S1PR3RARBRARARARG | |
| SCHEMBL15460636 | 0.90 | S1PR1 (0.33) | S1PR1S1PR3RARBRARARARG | |
| SCHEMBL19850724 | 0.86 | GRM2 (0.40) | S1PR1S1PR3RARBRARARARG | |
| SCHEMBL15783690 | 0.86 | MAOB (0.35) | S1PR1S1PR3RARBRARARARG | |
| SCHEMBL15461327 | 0.85 | KIF11 (0.40) | S1PR1RARBRARARARGTHRB | |
| SCHEMBL12623683 | 0.85 | S1PR1 (0.35) | S1PR1S1PR3RARBRARARARG | |
| SCHEMBL19844677 | 0.85 | FFAR1 (0.35) | S1PR1S1PR3RARBRARARARG | |
| SCHEMBL15460800 | 0.84 | ALOX5 (0.31) | S1PR1S1PR3RARB | |
| SCHEMBL19850759 | 0.84 | MAOB (0.40) | S1PR1S1PR3RARBRARARARG | |
| SCHEMBL15461038 | 0.84 | KIF11 (0.33) | S1PR1S1PR3RARBKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273245-B2 | Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-03-01 | — | — | US | disclosed |
| US-9273245-B2 | Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-03-01 | — | — | US | disclosed |
| US-20140034876-A1 | COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140034876-A1 | COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-02-06 | — | — | US | disclosed |