Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030476 | 0.87 | ABCB1 (0.46) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL2031216 | 0.87 | MAPT (0.35) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL2031985 | 0.86 | LMNA (0.38) | HPGDMEN1KMT2AMAPTGAA | |
| SCHEMBL2031420 | 0.85 | MAPKAPK2 (0.41) | HPGDMAPTGAAALDH1A1L3MBTL1 | |
| SCHEMBL2034749 | 0.85 | MAPKAPK2 (0.39) | HPGDMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2034779 | 0.84 | TP53 (0.41) | MAPTSMN1; SMN2ABCB1ABCG2 | |
| SCHEMBL998363 | 0.82 | KIF11 (0.42) | HPGDMAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL2029023 | 0.81 | STAT3 (0.38) | HPGDMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL2030157 | 0.81 | MAPT (0.37) | MAPTALDH1A1SMN1; SMN2ABCB1ABCG2 | |
| SCHEMBL997940 | 0.80 | KIF11 (0.44) | MAPTALDH1A1SMN1; SMN2ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829874-B1 | TRICYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO (JP) | 2014-02-12 | — | — | EP | claimed |