Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 17/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14739115 | 0.83 | GPR17 (0.67) | GPR17FBP1 | |
| SCHEMBL15463511 | 0.77 | GPR17 (0.66) | GPR17FBP1 | |
| SCHEMBL15463517 | 0.72 | GPR17 (0.66) | GPR17FBP1 | |
| SCHEMBL15463476 | 0.70 | GPR17 (0.66) | GPR17FBP1 | |
| SCHEMBL15463521 | 0.70 | GPR17 (0.66) | GPR17FBP1 | |
| SCHEMBL15463467 | 0.70 | GPR17 (0.66) | GPR17FBP1 | |
| SCHEMBL9234284 | 0.65 | PTGS1 (0.43) | GPR17 | |
| SCHEMBL14739207 | 0.63 | GPR17 (1.00) | GPR17FBP1 | |
| SCHEMBL15463512 | 0.63 | GPR17 (0.66) | GPR17 | |
| SCHEMBL15463450 | 0.63 | GPR17 (0.66) | GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567698-B1 | GPR 17 agonists and screening assay | UNIV BONN (DE) | 2014-02-12 | — | — | EP | claimed |