Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 12/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.66 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30559677 | 0.80 | GPR17 (1.00) | GPR17FBP1GRIN1 | |
| SCHEMBL8463078 | 0.80 | GPR17 (1.00) | GPR17FBP1GRIN1 | |
| SCHEMBL15463507 | 0.79 | GPR17 (0.66) | GPR17 | |
| SCHEMBL15463544 | 0.77 | GPR17 (0.46) | GPR17FBP1 | |
| SCHEMBL15463521 | 0.76 | GPR17 (0.66) | GPR17FBP1HPGD | |
| SCHEMBL15463517 | 0.76 | GPR17 (0.66) | GPR17FBP1HPGD | |
| SCHEMBL15463467 | 0.76 | GPR17 (0.66) | GPR17FBP1 | |
| SCHEMBL15463476 | 0.76 | GPR17 (0.66) | GPR17FBP1 | |
| SCHEMBL15463559 | 0.75 | GPR17 (0.69) | GPR17FBP1CYP1A2CYP2C9 | |
| SCHEMBL9078457 | 0.73 | GPR17 (0.58) | GPR17FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567698-B1 | GPR 17 agonists and screening assay | UNIV BONN (DE) | 2014-02-12 | — | — | EP | claimed |