SCHEMBL15463596

SCHEMBL15463596

O=[C]c1cc([C]=O)c(F)c([C]=O)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2550076 0.74 CES2 (0.42)
SCHEMBL356245 0.71
SCHEMBL96268 0.71 CES2 (0.39)
SCHEMBL2138209 0.70 CES2 (0.33)
SCHEMBL7700727 0.67 TRPV4 (0.33)
SCHEMBL9209444 0.67 HDAC1 (0.31)
SCHEMBL10651560 0.67
SCHEMBL7171797 0.67
SCHEMBL10607158 0.65 MEN1 (0.31)
SCHEMBL8903016 0.65 GRIN2D (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160074817-A1 Halogen Resistant Amides, Polyamides, and Membranes Made From the Same THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 2016-03-17 US claimed
US-9056284-B2 Chlorine resistant amides, polyamides, and membranes made from the same THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 2015-06-16 US claimed
US-20140263024-A1 HALOGEN RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK (US) 2014-09-18 US claimed
US-20140042082-A1 CHLORINE RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR 2014-02-13 US claimed
US-9056284-B2 Chlorine resistant amides, polyamides, and membranes made from the same THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 2015-06-16 US disclosed
US-20140263024-A1 HALOGEN RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME MURPHY ANDREW PATRICK (US) 2014-09-18 US disclosed
US-20140042082-A1 CHLORINE RESISTANT AMIDES, POLYAMIDES, AND MEMBRANES MADE FROM THE SAME THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE INTERIOR 2014-02-13 US disclosed