SCHEMBL15465982

SCHEMBL15465982

CCOc1ccc2c3ccccc3n(C)c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
HPGD P15428 4/20 0.54
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
HSD17B10 Q99714 2/20 0.54
HTT P42858 1/20 0.54
GPR3 P46089 1/20 0.53
KIF11 P52732 1/20 0.49
LMNA P02545 3/20 0.48
TSHR P16473 1/20 0.48
PSEN1 P49768 8/20 0.47
PSEN2 P49810 8/20 0.47
APH1B Q8WW43 8/20 0.47
NCSTN Q92542 8/20 0.47
APH1A Q96BI3 8/20 0.47
PSENEN Q9NZ42 8/20 0.47
NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15466592 0.90 MAPT (0.68) MAPTHPGDKDM4EALDH1A1L3MBTL1
SCHEMBL12722499 0.82 KDM4E (0.47) MAPTHPGDKDM4EALDH1A1L3MBTL1
SCHEMBL15466009 0.82 TP53 (0.59) MAPTHPGDKDM4EALDH1A1MEN1
SCHEMBL24439858 0.82 PSEN1 (0.70) MAPTHPGDKDM4EALDH1A1L3MBTL1
SCHEMBL29605147 0.82 PSEN1 (0.70) MAPTHPGDKDM4EALDH1A1L3MBTL1
SCHEMBL8086565 0.81 L3MBTL1 (0.56) MAPTHPGDKDM4EALDH1A1L3MBTL1
SCHEMBL15465809 0.81 L3MBTL1 (0.80) MAPTHPGDKDM4EALDH1A1L3MBTL1
SCHEMBL29606060 0.80 PSEN1 (0.66) MAPTHPGDKDM4EALDH1A1MEN1
SCHEMBL24439861 0.80 PSEN1 (0.66) MAPTHPGDKDM4EALDH1A1MEN1
SCHEMBL1180578 0.78 KDM4E (0.46) MAPTHPGDKDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220102653-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-03-31 US disclosed
US-10043978-B2 Organic semiconductor formulations FLEXTERRA, INC. (US) 2018-08-07 US disclosed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US disclosed
US-9293711-B2 Organic semiconductor formulations POLYERA CORPORATION (US) 2016-03-22 US disclosed
US-20140042369-A1 Organic Semiconductor Formulations USINVEST LLC 2014-02-13 US disclosed