SCHEMBL8086565

SCHEMBL8086565

CCOc1ccc2c(c1)c(=O)c1ccccc1n2C

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.56
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
MAPT P10636 5/20 0.53
ALDH1A1 P00352 3/20 0.53
KDM4E B2RXH2 2/20 0.53
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53
HSD17B10 Q99714 1/20 0.53
LMNA P02545 1/20 0.52
ATM Q13315 1/20 0.50
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
HCRTR1 O43613 2/20 0.48
THRB P10828 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15466592 0.88 MAPT (0.68) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL14280397 0.85 PSEN1 (0.52) ALDH1A1NPC1
SCHEMBL14280395 0.85 L3MBTL1 (0.51) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL26229304 0.83 MAPT (0.48) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL6152266 0.83 L3MBTL1 (0.76) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL11384587 0.83 XDH (0.52) L3MBTL1KMT2AMAPTALDH1A1HTT
SCHEMBL11387448 0.82 L3MBTL1 (0.51) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL11385638 0.82 HPGD (0.54) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL15465982 0.81 MAPT (0.54) L3MBTL1MEN1KMT2AMAPTALDH1A1
SCHEMBL11388007 0.81 FGFR1 (0.51) L3MBTL1MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6054501-A CURABILITY; GLOSSINESS; CAN BE BLENDED WITH INKS, PAINTS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
EP-0844255-A1 PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed