SCHEMBL15466535

SCHEMBL15466535

C1=CC2CC1CC2C1CC2CC1C1CCCCC21

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SGMS1 Q86VZ5 1/20 0.30
SGMS2 Q8NHU3 1/20 0.30
CA12 O43570 1/20 0.30
GMNN O75496 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
CA9 Q16790 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15466596 0.96 MAPT (0.33) SGMS1SGMS2CA12GMNNALDH1A1
SCHEMBL28367030 0.88 EPAS1 (0.30)
SCHEMBL409464 0.79 HSD11B1 (0.32) ALDH1A1LMNATDP1
SCHEMBL23629683 0.78
SCHEMBL961444 0.78 KDM4E (0.39) ALDH1A1LMNATDP1
SCHEMBL249375 0.77 HSD11B1 (0.35) ALDH1A1LMNATDP1
SCHEMBL250942 0.77 HSD11B1 (0.35) ALDH1A1LMNATDP1
SCHEMBL15467047 0.74
SCHEMBL7535152 0.74 KDM4E (0.32) ALDH1A1LMNATDP1
SCHEMBL15466664 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2019-03-12 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
EP-2870129-B1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION SUMITOMO BAKELITE CO (JP) 2016-04-06 EP disclosed
EP-2870129-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION Promerus, LLC (US) 2015-05-13 EP disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
WO-2014025735-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION NOTUM, AGPS, WEE1 SGMS1 66/4885SGMS2 41/4885CA12 893/4885
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation NOTUM, AGPS, WEE1 SGMS1 66/4885SGMS2 41/4885CA12 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.