SCHEMBL961444

SCHEMBL961444

C1=CC2CC1CC2C1CC2C=CC1C2

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 3/20 0.38
GAA P10253 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
EPHX2 P34913 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15467194 0.79 ALDH1A1 (0.37) ALDH1A1GAATDP1EPHX2
SCHEMBL7535152 0.79 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL409464 0.79 HSD11B1 (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL553412 0.79 ALDH1A1 (0.38) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL5703487 0.79 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL19035911 0.79 KDM4E (0.32) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL15467232 0.79 ALDH1A1 (0.33) KDM4ELMNAALDH1A1GAATDP1
SCHEMBL15466872 0.78 ALDH1A1 (0.43) ALDH1A1GAATDP1EPHX2
SCHEMBL15466596 0.78 MAPT (0.33) KDM4ELMNAALDH1A1TDP1
SCHEMBL15467125 0.78 ALDH1A1 (0.30) ALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240110003-A1 FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC FUNCTIONALITY FOR FORMING LOW-LOSS FILMS HAVING IMPROVED DIELECTRIC AND THERMAL PROPERTIES PROMERUS, LLC (US) 2024-04-04 US claimed
EP-4237460-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES Promerus, LLC (US) 2023-09-06 EP claimed
WO-2022094232-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2022-05-05 WO claimed
US-7666966-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2010-02-23 US claimed
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PROMERUS, LLC (US) 2025-12-25 US disclosed
CN-118222091-A Resin composition, laminate, prepreg, cured product, substrate with cured product, and electronic device 爱天思株式会社 2024-06-21 CN disclosed
WO-2023189302-A1 RESIN COMPOSITION, MOLDED ARTICLE, AND OPTICAL MEMBER 日本ゼオン株式会社 2023-10-05 WO disclosed
EP-4237460-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES Promerus, LLC (US) 2023-09-06 EP disclosed
EP-4237461-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS Promerus, LLC (US) 2023-09-06 EP disclosed
US-11667754-B2 Tetracarboxylic dianhydride, carbonyl compound, polyimide precursor resin, and polyimide ENEOS CORPORATION (JP) 2023-06-06 US disclosed
WO-2022094236-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS PROMERUS, LLC (US) 2022-05-05 WO disclosed
WO-2022094232-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2022-05-05 WO disclosed
US-7476716-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2009-01-13 US disclosed
EP-1535941-B1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORP (JP) 2007-09-12 EP disclosed
US-20070191563-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2007-08-16 US disclosed
EP-1706374-A2 NORBORNANE BASED CYCLOALIPHATIC COMPOUNDS CONTAINING NITRILE GROUPS INVISTA NORTH AMERICA S.A R.L. (US) 2006-10-04 EP disclosed
US-20060211834-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2006-09-21 US disclosed
WO-2005075412-A2 NORBORNANE BASED CYCLOALIPHATIC COMPOUNDS CONTAINING NITRILE GROUPS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-08-18 WO disclosed
US-20050159614-A1 Norbornane based cycloaliphatic compounds containing nitrile groups E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-21 US disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667754-B2 Tetracarboxylic dianhydride, carbonyl compound, polyimide precursor resin, and polyimide ELL, EED, DIS3 KDM4E 713/4885LMNA 1568/4885ALDH1A1 3467/4885
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PYM1, TAAR1, RAD52 KDM4E 745/4885LMNA 539/4885ALDH1A1 2254/4885
US-20050159614-A1 Norbornane based cycloaliphatic compounds containing nitrile groups NISCH, PAH, CYP1B1 KDM4E 4004/4885LMNA 4230/4885ALDH1A1 2222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.