Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794397 | 0.93 | KCNH2 (0.44) | KCNH2MCHR1CYP2D6PKMCYP2C19 | |
| SCHEMBL794053 | 0.91 | KCNH2 (0.44) | KCNH2MCHR1CYP2D6PKMCYP2C19 | |
| SCHEMBL15467187 | 0.90 | EPHX2 (0.45) | KCNH2MCHR1EPHX2CCR2 | |
| SCHEMBL15466459 | 0.90 | KCNH2 (0.39) | KCNH2MCHR1EPHX2KMT2ACCR2 | |
| SCHEMBL794099 | 0.89 | EPHX2 (0.41) | KCNH2MCHR1EPHX2P2RX7NR1H4 | |
| SCHEMBL15466506 | 0.88 | EPHX2 (0.42) | KCNH2MCHR1EPHX2P2RX7NR1H4 | |
| SCHEMBL797804 | 0.87 | EPHX2 (0.44) | KCNH2MCHR1EPHX2 | |
| SCHEMBL18229242 | 0.86 | AR (0.42) | KCNH2MCHR1CYP2D6PKMCYP2C19 | |
| SCHEMBL18227011 | 0.86 | AR (0.42) | KCNH2MCHR1CYP2D6PKMCYP2C19 | |
| SCHEMBL794609 | 0.85 | EPHX2 (0.40) | KCNH2MCHR1CYP2D6PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | KCNH2 177/4885MCHR1 1165/4885CYP2D6 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.