Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | GAA | P10253 | 3/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | NPY1R | P25929 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13248361 | 0.82 | KMT2A (0.73) | KMT2AKDM4EALDH1A1MEN1GAA | |
| SCHEMBL15466900 | 0.75 | KDM4E (0.61) | KMT2AKDM4EALDH1A1MEN1GAA | |
| SCHEMBL28827974 | 0.69 | KDM4E (0.72) | KMT2AKDM4EALDH1A1MEN1GAA | |
| SCHEMBL10838568 | 0.67 | APP (0.74) | — | |
| SCHEMBL10839105 | 0.66 | APP (0.70) | KMT2AMEN1HTT | |
| SCHEMBL30125140 | 0.66 | APP (0.70) | KMT2AMEN1HTT | |
| SCHEMBL8609424 | 0.66 | POLB (0.68) | KMT2AKDM4EALDH1A1GAAPOLB | |
| SCHEMBL17770433 | 0.65 | PDE5A (0.73) | KMT2AKDM4EALDH1A1MEN1POLB | |
| SCHEMBL18934419 | 0.64 | KDM4E (0.74) | KMT2AKDM4EALDH1A1MEN1GAA | |
| SCHEMBL13740867 | 0.64 | KMT2A (0.56) | KMT2AKDM4EALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045779-A1 | COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION | XU LIFENG (US) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045779-A1 | COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION | ALPI, SI, SLC5A11 | KMT2A 4631/4885KDM4E 2909/4885ALDH1A1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.