Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15473498 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL15466789 | 0.75 | KMT2A (0.77) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28064491 | 0.72 | KMT2A (0.72) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL13248361 | 0.70 | KMT2A (0.73) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28064412 | 0.69 | KDM4E (0.88) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL3173789 | 0.67 | ADORA2A (0.55) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL3455848 | 0.64 | HPGD (1.00) | ALDH1A1KMT2AMEN1HPGDPOLB | |
| SCHEMBL8621356 | 0.64 | HPGD (0.76) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL28064492 | 0.63 | HDAC1 (0.66) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28064513 | 0.63 | HDAC1 (0.65) | KDM4EALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045779-A1 | COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION | XU LIFENG (US) | 2014-02-13 | — | — | US | claimed |
| US-20140045779-A1 | COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION | XU LIFENG (US) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045779-A1 | COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION | ALPI, SI, SLC5A11 | KDM4E 2909/4885ALDH1A1 1864/4885KMT2A 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.