Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 7/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808119 | 0.84 | CTSB (0.37) | CRHR1RXFP1EPHX2KMT2AMAPT | |
| SCHEMBL799020 | 0.82 | RXFP1 (0.35) | CRHR1RXFP1EPHX2KMT2AMAPT | |
| SCHEMBL807620 | 0.81 | NR1H2 (0.36) | RXFP1EPHX2PTGES | |
| SCHEMBL20631225 | 0.75 | AR (0.42) | EPHX2KMT2ACYP2D6PKMCYP2C19 | |
| SCHEMBL22548984 | 0.75 | AR (0.42) | EPHX2KMT2ACYP2D6PKMCYP2C19 | |
| SCHEMBL25277402 | 0.75 | AR (0.42) | EPHX2KMT2ACYP2D6PKMCYP2C19 | |
| SCHEMBL20631667 | 0.75 | AR (0.42) | EPHX2KMT2ACYP2D6PKMCYP2C19 | |
| SCHEMBL20631666 | 0.75 | AR (0.42) | EPHX2KMT2ACYP2D6PKMCYP2C19 | |
| SCHEMBL17874617 | 0.75 | AR (0.42) | EPHX2KMT2ACYP2D6PKMCYP2C19 | |
| SCHEMBL20633240 | 0.75 | AR (0.42) | EPHX2KMT2ACYP2D6PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | CRHR1 2191/4885AADAT 1692/4885RXFP1 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.