Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HEXA | P06865 | 2/20 | 0.37 |
| ▸ | HEXB | P07686 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22702280 | 0.86 | PLA2G7 (0.49) | PLA2G7HDAC6RECQLALDH1A1HEXA | |
| SCHEMBL13204644 | 0.82 | MGLL (0.47) | PLA2G7HDAC6ALDH1A1NR1H2NR1H3 | |
| SCHEMBL11252578 | 0.81 | MGLL (0.50) | PLA2G7ALDH1A1PDE5AFAAHMGLL | |
| SCHEMBL30372493 | 0.81 | MGLL (0.50) | PLA2G7ALDH1A1PDE5AFAAHMGLL | |
| SCHEMBL11264830 | 0.81 | MGLL (0.50) | PLA2G7ALDH1A1PDE5AFAAHMGLL | |
| SCHEMBL17213445 | 0.80 | PLA2G7 (0.47) | PLA2G7HDAC6RECQLALDH1A1NR1H2 | |
| SCHEMBL9190811 | 0.78 | PLA2G7 (0.46) | PLA2G7HDAC6RECQLALDH1A1NR1H2 | |
| SCHEMBL13204456 | 0.77 | HRH3 (0.47) | PLA2G7HDAC6ALDH1A1HRH1GAA | |
| SCHEMBL13204370 | 0.77 | KCNH2 (0.43) | PLA2G7ALDH1A1USP2HTR1ADRD2 | |
| SCHEMBL21927803 | 0.76 | PLA2G7 (0.44) | PLA2G7HDAC6RECQLALDH1A1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678349-B1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-01-13 | — | — | EP | disclosed |
| US-9139609-B2 | C-4″ position substituted macrolide derivative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046043-A1 | C-4\" POSITION SUBSTITUTED MACROLIDE DERIVATIVE | MRPL21, MRPS34, MRPL37 | PLA2G7 4284/4885HDAC6 783/4885RECQL 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.