Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781370 | 0.87 | KDM4E (0.85) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL11213828 | 0.85 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL11212983 | 0.85 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL11215130 | 0.85 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL11213832 | 0.83 | RAB9A (0.77) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL11464717 | 0.83 | SREBF2 (0.79) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL13480645 | 0.80 | KDM4E (1.00) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL68135 | 0.80 | KDM4E (1.00) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL23742623 | 0.79 | RAB9A (0.63) | KDM4EKMT2AARSREBF2RAB9A | |
| SCHEMBL6200227 | 0.78 | AR (0.52) | KDM4EKMT2AARSREBF2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9301424-B2 | Auto-compensating temperature valve controller for electro-rheological fluid micro-channel cooled integrated circuit | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-03-29 | — | — | US | disclosed |
| US-9257366-B2 | Auto-compensating temperature valve controller for electro-rheological fluid micro-channel cooled integrated circuit | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2016-02-09 | — | — | US | disclosed |
| US-20160037682-A1 | Auto-Compensating Temperature Valve Controller for Electro-Rheological Fluid Micro-Channel Cooled Integrated Circuit | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2016-02-04 | — | — | US | disclosed |
| US-9052724-B2 | Electro-rheological micro-channel anisotropic cooled integrated circuits and methods thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150116939-A1 | Auto-Compensating Temperature Valve Controller for Electro-Rheological Fluid Micro-Channel Cooled Integrated Circuit | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-04-30 | — | — | US | disclosed |
| US-20140043757-A1 | ELECTRO-RHEOLOGICAL MICRO-CHANNEL ANISOTROPIC COOLED INTEGRATED CIRCUITS AND METHODS THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-02-13 | — | — | US | disclosed |