SCHEMBL11213832

SCHEMBL11213832

c1ccc(-c2nc(-c3ccccc3-c3csc(-c4ccccc4)n3)cs2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.77
SMN1; SMN2 Q16637 7/20 0.77
CASP3 P42574 1/20 0.77
SENP8 Q96LD8 1/20 0.77
SENP7 Q9BQF6 1/20 0.77
SENP6 Q9GZR1 1/20 0.77
NPC1 O15118 6/20 0.70
KDM4E B2RXH2 6/20 0.67
KMT2A Q03164 3/20 0.67
AR P10275 1/20 0.67
SREBF2 Q12772 1/20 0.62
MAPT P10636 3/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
CYP19A1 P11511 2/20 0.61
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 2/20 0.57
HPGD P15428 2/20 0.57
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.57
GAA P10253 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17336572 0.87 RAB9A (0.66) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL13379242 0.87 RAB9A (1.00) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL11533708 0.87 RAB9A (0.66) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL1206993 0.87 RAB9A (0.66) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL2781370 0.87 KDM4E (0.85) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL11765529 0.87 RAB9A (0.58) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL11215130 0.85 SREBF2 (0.82) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL11212983 0.85 SREBF2 (0.82) RAB9ASMN1; SMN2CASP3SENP8SENP7
SCHEMBL11213828 0.85 SREBF2 (0.82) RAB9ASMN1; SMN2CASP3SENP8SENP7
Anthraquinone SCHEMBL15467640 0.83 KDM4E (0.67) RAB9ASMN1; SMN2CASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4258116-A ORGANIC SEMICONDUCTOR CANON KABUSHIKI KAISHA (JP) 1981-03-24 US claimed
US-4341853-A Spectral sensitization of organic photoconductors with diazastryl dyes FUJI PHOTO FILM CO., LTD. (JP) 1982-07-27 US disclosed
US-4334001-A Azacyanine spectra sensitized organic photoconductive compositions and elements FUJI PHOTO FILM CO., LTD. (JP) 1982-06-08 US disclosed
US-4042388-A FREE RADICAL FORMERS, DYES CANON KABUSHIKI KAISHA (JA) 1977-08-16 US disclosed