Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794326 | 0.92 | RXFP1 (0.36) | TSHRKMT2ARXFP1EPHX2CYP2C9 | |
| SCHEMBL798260 | 0.91 | ATF1 (0.40) | TSHRKMT2ARXFP1EPHX2CYP2C9 | |
| SCHEMBL15466297 | 0.89 | TSHR (0.37) | TSHRKMT2ARXFP1EPHX2CYP2C9 | |
| SCHEMBL15466559 | 0.89 | NR1H2 (0.36) | TSHRCYP2C9CAMK1DNR1H2NR1H3 | |
| SCHEMBL794978 | 0.89 | NR1H2 (0.43) | TSHRCYP2C9CAMK1DNR1H2NR1H3 | |
| SCHEMBL793870 | 0.85 | TSHR (0.40) | TSHRKMT2ARXFP1EPHX2CYP2C9 | |
| SCHEMBL807955 | 0.84 | EPHX2 (0.40) | TSHRKMT2AEPHX2CYP2C9CCR2 | |
| SCHEMBL17857816 | 0.82 | EPHX2 (0.35) | RXFP1EPHX2CYP2C9KDM4ENR1H2 | |
| SCHEMBL3030705 | 0.81 | NR1H2 (0.35) | EPHX2NR1H2NR1H3 | |
| SCHEMBL796012 | 0.80 | CCR4 (0.35) | RXFP1EPHX2CYP2C9KDM4EKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | TSHR 356/4885KMT2A 2333/4885RXFP1 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.