Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.39 |
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793659 | 0.92 | KCNH2 (0.39) | KCNH2MCHR1EPHX2CYP2C9RXFP1 | |
| SCHEMBL15467466 | 0.91 | KCNH2 (0.40) | TSHRKMT2AKCNH2MCHR1EPHX2 | |
| SCHEMBL795833 | 0.89 | CYP1A2 (0.34) | TSHRMCHR1CYP2C9 | |
| SCHEMBL795686 | 0.89 | NR1H2 (0.34) | TSHRMCHR1EPHX2KDM4E | |
| SCHEMBL15467718 | 0.85 | TSHR (0.38) | TSHRKMT2AKCNH2MCHR1EPHX2 | |
| SCHEMBL807955 | 0.83 | EPHX2 (0.40) | TSHRKMT2AKCNH2MCHR1EPHX2 | |
| SCHEMBL15467187 | 0.82 | EPHX2 (0.45) | KCNH2MCHR1EPHX2CCR2CYP2C9 | |
| SCHEMBL807886 | 0.82 | SCD (0.43) | TSHRMCHR1CYP2C9 | |
| SCHEMBL794660 | 0.82 | EPHX2 (0.37) | KMT2AKCNH2MCHR1EPHX2CYP2C9 | |
| SCHEMBL15466705 | 0.82 | KCNH2 (0.48) | KMT2AKCNH2MCHR1EPHX2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | TSHR 356/4885KMT2A 2333/4885KCNH2 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.