Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26287640 | 0.91 | PTPN1 (0.46) | ALDH1A1SYNJ2HTTSLC22A1LMNA | |
| SCHEMBL15468167 | 0.89 | TSHR (0.51) | ALDH1A1TSHRLMNAPOLBGAA | |
| SCHEMBL6377053 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL5974842 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL5974836 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL7215485 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL4263976 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL6377056 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL22758821 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 | |
| SCHEMBL7215482 | 0.88 | PTPN1 (0.47) | ALDH1A1TSHRLMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648188-B2 | Preparation of 2-chloro-9-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-adenine | SCINOPHARM TAIWAN, LTD. (TW) | 2014-02-11 | — | — | US | disclosed |