Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16756804 | 0.87 | POLB (0.50) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL26906433 | 0.87 | POLB (0.50) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL15480819 | 0.87 | POLB (0.50) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL21894771 | 0.87 | POLB (0.50) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| Bromide SCHEMBL6394977 | 0.86 | POLB (0.49) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| Bromide SCHEMBL5004971 | 0.86 | POLB (0.49) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL8357802 | 0.84 | TSHR (0.51) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL18880006 | 0.83 | KMT2A (0.48) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL15468162 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAPOLBKMT2AMAPK1 | |
| SCHEMBL17359607 | 0.81 | LMNA (0.45) | ALDH1A1LMNAPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648188-B2 | Preparation of 2-chloro-9-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-adenine | SCINOPHARM TAIWAN, LTD. (TW) | 2014-02-11 | — | — | US | disclosed |