SCHEMBL15468308

SCHEMBL15468308

CC(C)[C@@H]1CO[C@@H]2C[C@H](C)C(=O)N21

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060274 0.83 PIK3CD (0.33) PIK3CD
SCHEMBL10060269 0.76 FAP (0.36) PIK3CD
SCHEMBL10079279 0.76 FAP (0.31) PIK3CD
SCHEMBL10060266 0.73 FAP (0.32) PIK3CD
SCHEMBL10060267 0.68 FAP (0.36) PIK3CD
SCHEMBL16589453 0.66 KMT2A (0.34) PIK3CD
SCHEMBL10060257 0.66 FAP (0.31) PIK3CD
SCHEMBL10060283 0.65 OPRM1 (0.35)
SCHEMBL10079646 0.65 OPRM1 (0.35)
SCHEMBL10079286 0.62 FAP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8648094-B2 IAP BIR domain binding compounds PHARMASCIENCE, INC. (CA) 2014-02-11 US disclosed