Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992786 | 0.88 | ESRRG (0.51) | ESRRGHDAC1HDAC3MAPTTP53 | |
| SCHEMBL10170740 | 0.86 | ESRRG (0.48) | ESRRGHDAC1HDAC3MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL992071 | 0.85 | ESRRG (0.47) | ESRRGHDAC1HDAC3MAPTTP53 | |
| SCHEMBL2681261 | 0.81 | SMN1; SMN2 (0.54) | ESRRGHDAC1HDAC3MAPTNPC1 | |
| SCHEMBL3065309 | 0.77 | RAB9A (0.70) | HDAC1HDAC3NPC1RAB9AHDAC6 | |
| SCHEMBL14219257 | 0.77 | NR1H4 (0.61) | ESRRGMAPTTP53NPC1RAB9A | |
| SCHEMBL12462055 | 0.75 | MAOB (0.64) | HDAC1HDAC3MAPTTP53LMNA | |
| SCHEMBL28238457 | 0.74 | L3MBTL1 (0.58) | HDAC3TP53GAALMNAALDH1A1 | |
| SCHEMBL12988882 | 0.73 | L3MBTL1 (0.57) | ESRRGHDAC1HDAC3GAAALDH1A1 | |
| SCHEMBL13177792 | 0.73 | HDAC2 (0.63) | MAPTNPC1RAB9AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648201-B2 | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH (DE) | 2014-02-11 | — | — | US | disclosed |