Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 14/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322731 | 0.92 | DPP8 (0.38) | DPP7DPP4F2DPP8DPP9 | |
| SCHEMBL24322781 | 0.77 | DPP8 (0.44) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL10730573 | 0.77 | DPP8 (0.44) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL6820644 | 0.76 | DPP7 (0.56) | DPP7DPP4DPP8DPP9CA12 | |
| SCHEMBL6823435 | 0.76 | DPP7 (0.56) | DPP7DPP4DPP8DPP9CA12 | |
| SCHEMBL19309525 | 0.75 | ITGB3 (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL24322721 | 0.74 | GAA (0.47) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL24324302 | 0.74 | DPP7 (0.38) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL11534938 | 0.74 | GAA (0.47) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL27296297 | 0.74 | ARG1 (0.35) | DPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046393-B1 | CONTROLLED RELEASE OF PHENOLIC OPIOIDS | SIGNATURE THERAPEUTICS INC (US) | 2014-02-12 | — | — | EP | disclosed |