Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.58 |
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20576195 | 0.92 | MAPK1 (0.57) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL6201307 | 0.91 | CES2 (0.58) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL10392118 | 0.91 | CES2 (0.54) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL142538 | 0.90 | CES2 (0.74) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL29989494 | 0.90 | CES2 (0.74) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL142537 | 0.90 | CES2 (0.74) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL11484197 | 0.88 | CES2 (0.59) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL11484209 | 0.88 | CES2 (0.59) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL5444947 | 0.86 | HPGD (0.62) | CES2CES1ALDH1A1MAPTMDM2 | |
| SCHEMBL7090969 | 0.86 | AKR1C3 (0.49) | CES2CES1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740547-A | Aromatic polysulfone thermoplastics protected from discoloration during thermal processing | BORG-WARNER CHEMICALS, INC. (US) | 1988-04-26 | — | — | US | claimed |
| US-4740548-A | Polyimide thermoplastic protected from discoloration during thermal processing | BORG-WARNER CHEMICALS, INC. (US) | 1988-04-26 | — | — | US | claimed |
| US-4695601-A | A-HYDROXYKETONE | BORG-WARNER CHEMICALS, INC. (US) | 1987-09-22 | — | — | US | claimed |
| US-4130567-A | Process for the preparation of aryl dioxolanes | SUN CHEMICAL CORPORATION (US) | 1978-12-19 | — | — | US | claimed |
| JP-58132589-A | — | — | None | — | — | JP | disclosed |
| JP-4063801-A | — | — | None | — | — | JP | disclosed |
| WO-2023070903-A1 | AROMATIC ALDEHYDE CONDENSATION METHOD | 台州学院 | 2023-05-04 | — | — | WO | disclosed |
| CN-110452148-B | Method for synthesizing polysubstituted pyrrole compound by utilizing alpha-hydroxy ketone, malononitrile and alcohol | 华南理工大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-113896622-A | Condensation method of aromatic aldehyde | 台州学院 | 2022-01-07 | — | — | CN | disclosed |
| US-10844051-B2 | Substituted oxazoles for the treatment of cancer | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY | 2020-11-24 | — | — | US | disclosed |
| US-10059700-B2 | Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction | SEKISUI CHEMICAL CO., LTD. (JP) | 2018-08-28 | — | — | US | disclosed |
| US-20180208586-A1 | COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCERS AND OTHER MEDICAL CONDITIONS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-07-26 | — | — | US | disclosed |
| US-4130567-A | Process for the preparation of aryl dioxolanes | SUN CHEMICAL CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4028412-A | BENZOIN OXIMES FOR COPPER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-06-07 | — | — | US | disclosed |
| US-4014889-A | Process for preparing ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
| US-4013643-A | N,N-DISUBSTITUTED 2,3-DIPHENYLALLYLAMINES | G. D. SEARLE & CO. (US) | 1977-03-22 | — | — | US | disclosed |
| US-4007209-A | OF BENZOINS | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
| US-3937722-A | PHOTOSENSITIZERS, IRRADIATION POLYMERIZATION, CROSSLINKING | BAYER AG (DT) | 1976-02-10 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208586-A1 | COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCERS AND OTHER MEDICAL CONDITIONS | VHL, TP53, CD44 | CES2 915/4885CES1 1052/4885LMNA 1482/4885 |
| US-10844051-B2 | Substituted oxazoles for the treatment of cancer | OXA1L, PDCD1, MCL1 | CES2 2724/4885CES1 2495/4885LMNA 4635/4885 |
| US-10059700-B2 | Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction | ALDH2, ALDH7A1, ALDH3A1 | CES2 1248/4885CES1 2376/4885LMNA 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.