Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307799 | 0.86 | MAPT (0.46) | FOLH1CYP2C19HDAC3HDAC4HDAC1 | |
| SCHEMBL14027320 | 0.84 | ALDH1A1 (0.42) | FOLH1CYP2C19PPARGPPARAATM | |
| SCHEMBL15468646 | 0.78 | CYSLTR2 (0.38) | CYP2C19HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15468633 | 0.77 | GSTK1 (0.32) | — | |
| SCHEMBL15468649 | 0.76 | CYP2C19 (0.39) | CYP2C19MAPTSMN1; SMN2 | |
| Cpi 613 SCHEMBL1062218 | 0.71 | CYP2C19 (0.59) | FOLH1CYP2C19HDAC3HDAC4HDAC1 | |
| Cpi 613 SCHEMBL13333201 | 0.71 | CYP2C19 (0.59) | FOLH1CYP2C19HDAC3HDAC4HDAC1 | |
| SCHEMBL3713575 | 0.71 | MAPT (0.47) | CYP2C19HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22299081 | 0.70 | CYP2C19 (0.58) | FOLH1CYP2C19HDAC3HDAC4HDAC1 | |
| SCHEMBL10454113 | 0.70 | CYP2C19 (0.46) | FOLH1CYP2C19HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2695614-A1 | Lipoic acid derivatives | Cornerstone Pharmaceuticals, Inc. (US) | 2014-02-12 | — | — | EP | disclosed |