SCHEMBL15468697

SCHEMBL15468697

O=C(NC1CCCc2ccccc21)C(F)(F)S(=O)(=O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.56
ALDH1A1 P00352 2/20 0.55
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
EPHX1 P07099 1/20 0.54
LMNA P02545 2/20 0.54
TAS1R3 Q7RTX0 5/20 0.53
TAS1R1 Q7RTX1 5/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TAS1R2 Q8TE23 4/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
HPGD P15428 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1266129 0.85 HTT (0.63) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL606392 0.85 HTT (0.63) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL15006999 0.85 HTT (0.63) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL10284322 0.82 TAS1R3 (0.50) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL14335627 0.80 HTT (0.63) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL16301130 0.80 HTT (0.63) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL15705319 0.78 HTT (0.68) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL13569354 0.77 HTT (0.64) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL599005 0.76 MTNR1A (0.57) HTTALDH1A1KMT2AMEN1EPHX1
SCHEMBL1987710 0.76 MTNR1A (0.57) HTTALDH1A1KMT2AMEN1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023579-B2 Actinic-ray- or radiation-sensitive resin composition, compound and method of forming pattern using the composition FUJIFILM CORPORATION (JP) 2015-05-05 US disclosed
US-8647812-B2 Pattern forming method, chemical amplification resist composition and resist film FUJIFILM CORPORATION (JP) 2014-02-11 US disclosed