SCHEMBL15469291

SCHEMBL15469291

CC1(C)c2cc(-c3ccc4ccccc4c3)ccc2N(c2ccc3ccccc3c2)c2ccc(-c3ccc4ccccc4c3)cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.42
POLB P06746 2/20 0.42
KMT2A Q03164 1/20 0.42
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
ALOX5 P09917 1/20 0.38
ALDH1A1 P00352 3/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
HTR3A P46098 2/20 0.37
CYP1A2 P05177 3/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
PTGER3 P43115 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15469284 0.94 HSP90AA1 (0.41) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL15469332 0.94 HSP90AA1 (0.41) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL15469276 0.94 HSP90AA1 (0.41) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL13557589 0.94 HSP90AA1 (0.41) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL15046215 0.92 KMT2A (0.37) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL15469330 0.91 LPL (0.41) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL15469329 0.91 LPL (0.40) POLBLPLLIPGESR1ESR2
SCHEMBL17206569 0.90 HSP90AA1 (0.38) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL13557632 0.90 LPL (0.40) HSP90AA1POLBKMT2ALPLLIPG
SCHEMBL19381066 0.90 ALDH1A1 (0.36) HSP90AA1POLBKMT2ALPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
EP-2703388-A1 COMPOUND WITH ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2014-03-05 EP disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed