Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.76 |
| ▸ | FAAH | O00519 | 5/20 | 0.69 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15469716 | 0.91 | FAAH (0.76) | CES1FAAH | |
| SCHEMBL15469722 | 0.89 | FAAH (0.74) | CES1FAAH | |
| SCHEMBL2775934 | 0.88 | CES1 (0.76) | CES1FAAHNCEH1 | |
| SCHEMBL2776361 | 0.86 | FAAH (0.73) | CES1FAAH | |
| SCHEMBL2772834 | 0.86 | CES1 (1.00) | CES1FAAH | |
| SCHEMBL15469711 | 0.84 | CES1 (0.74) | CES1FAAH | |
| SCHEMBL1471390 | 0.82 | FAAH (1.00) | CES1FAAH | |
| SCHEMBL2772759 | 0.80 | CES1 (0.83) | CES1FAAH | |
| SCHEMBL2772396 | 0.79 | FAAH (0.84) | CES1FAAH | |
| SCHEMBL12003044 | 0.79 | CES1 (0.71) | CES1FAAHNCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045800-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045800-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, APEH | CES1 107/4885FAAH 1/4885NCEH1 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.