SCHEMBL15469864

SCHEMBL15469864

c1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4ccc(-c5ccc6c(c5)Oc5ccccc5N6c5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.32
MGLL Q99685 2/20 0.32
ALDH1A1 P00352 2/20 0.32
HSP90AA1 P07900 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
ATM Q13315 1/20 0.32
P2RX4 Q99571 5/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CDK8 P49336 1/20 0.31
PDE6D O43924 1/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15469865 1.00 FAAH (0.32) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL15469917 0.99 FAAH (0.33) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL15469916 0.99 FAAH (0.33) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL15469856 0.99 P2RX4 (0.32) ALDH1A1P2RX4MAPTKDM4ECYP1A2
SCHEMBL14934719 0.99 P2RX4 (0.32) ALDH1A1P2RX4MAPTKDM4ECYP1A2
SCHEMBL15469888 0.97 FAAH (0.33) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL15469887 0.97 P2RX4 (0.31) FAAHMGLLALDH1A1P2RX4MAPT
SCHEMBL15469936 0.97 FAAH (0.34) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL15469934 0.96 FAAH (0.34) FAAHMGLLALDH1A1HSP90AA1PKM
SCHEMBL15469883 0.96 P2RX4 (0.31) ALDH1A1P2RX4MAPTKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed