SCHEMBL14934719

SCHEMBL14934719

c1ccc(N(c2ccc(-c3ccc4c(c3)Oc3ccccc3N4c3ccccc3)cc2)c2ccc(-c3ccc4c(c3)Oc3ccccc3N4c3ccccc3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 6/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CDK8 P49336 1/20 0.31
APP P05067 1/20 0.31
P2RX1 P51575 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15469856 1.00 P2RX4 (0.32) P2RX4MAPTKDM4EALDH1A1CYP1A2
SCHEMBL15469865 0.99 FAAH (0.32) P2RX4MAPTKDM4EALDH1A1CYP1A2
SCHEMBL15469864 0.99 FAAH (0.32) P2RX4MAPTKDM4EALDH1A1CYP1A2
SCHEMBL15469887 0.99 P2RX4 (0.31) P2RX4MAPTKDM4EALDH1A1CYP1A2
SCHEMBL15469883 0.97 P2RX4 (0.31) P2RX4MAPTKDM4EALDH1A1CYP1A2
SCHEMBL15469917 0.97 FAAH (0.33) P2RX4MAPTALDH1A1CDK8P2RX1
SCHEMBL15469916 0.97 FAAH (0.33) P2RX4MAPTALDH1A1CDK8P2RX1
SCHEMBL15469888 0.96 FAAH (0.33) P2RX4ALDH1A1APP
SCHEMBL15469936 0.96 FAAH (0.34) P2RX4MAPTALDH1A1CDK8P2RX1
SCHEMBL23220423 0.96 ALDH1A1 (0.34) MAPTKDM4EALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9735370-B2 Compound, device and method of making same CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-08-15 US disclosed
US-9735370-B2 Compound, device and method of making same CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-08-15 US disclosed
US-20140299868-A1 Compound, Device and Method of Making Same CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-10-09 US disclosed
US-20140299868-A1 Compound, Device and Method of Making Same CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-10-09 US disclosed
US-20140252339-A1 LIGHT EMITTING COMPOSITION AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-09-11 US disclosed
US-20140252339-A1 LIGHT EMITTING COMPOSITION AND DEVICE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-09-11 US disclosed
WO-2013064814-A1 LIGHT EMITTING COMPOSITION AND DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-05-10 WO disclosed
WO-2013064793-A1 COMPOUND, DEVICE AND METHOD OF MAKING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-05-10 WO disclosed