SCHEMBL15470265

SCHEMBL15470265

Cc1ccc2c(c1)Oc1cc(-c3ccccc3)ccc1N2c1ccc(-c2ccc(-c3cccc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 4/20 0.37
GGPS1 O95749 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 4/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAOB P27338 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
LMNA P02545 1/20 0.32
PPARG P37231 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
NR2E3 Q9Y5X4 1/20 0.32
NCOR2 Q9Y618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470263 0.95 ALOX5 (0.46) ALOX5PRKDCGGPS1L3MBTL1ALDH1A1
SCHEMBL15470261 0.94 ALOX5 (0.47) ALOX5PRKDCGGPS1ALDH1A1KDM4E
SCHEMBL15470262 0.91 ALOX5 (0.44) ALOX5PRKDCGGPS1ALDH1A1KDM4E
SCHEMBL24062446 0.90 ALOX5 (0.51) ALOX5PRKDCGGPS1ALDH1A1KDM4E
SCHEMBL24062434 0.90 ALOX5 (0.48) ALOX5PRKDCGGPS1ALDH1A1KDM4E
SCHEMBL15470266 0.88 ALOX5 (0.45) ALOX5PRKDCGGPS1ALDH1A1MAPT
SCHEMBL13827274 0.87 ALOX5 (0.48) ALOX5PRKDCGGPS1ALDH1A1KDM4E
SCHEMBL15470160 0.87 PLA2G2A (0.39) PRKDCL3MBTL1ALDH1A1MAPTKDM4E
SCHEMBL15470500 0.87 ALOX5 (0.41) ALOX5PRKDCGGPS1ALDH1A1KDM4E
SCHEMBL15470328 0.87 ALOX5 (0.43) ALOX5PRKDCGGPS1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed