SCHEMBL15470280

SCHEMBL15470280

c1ccc(-c2ccc3c(c2)Oc2cc(-c4cccc5ccccc45)ccc2N3c2ccc(-c3ccc(-c4cccc5c4sc4ccccc45)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
PRKDC P78527 6/20 0.39
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
PDE6D O43924 1/20 0.34
F9 P00740 1/20 0.34
S1PR4 O95977 3/20 0.33
S1PR5 Q9H228 3/20 0.33
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
DNPH1 O43598 1/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470276 0.94 ALOX5 (0.46) ALOX5PRKDCPDE6DF9DNPH1
SCHEMBL15470278 0.91 ALOX5 (0.44) ALOX5PRKDCPDE6DF9DNPH1
SCHEMBL15470488 0.90 PDE6D (0.36) ALOX5PRKDCCA12CA1CA2
SCHEMBL13827532 0.90 ALOX5 (0.47) ALOX5PRKDCPDE6DF9DNPH1
SCHEMBL15470281 0.88 ALOX5 (0.41) ALOX5PRKDCPDE6DF9DNPH1
SCHEMBL15470321 0.87 ALOX5 (0.45) ALOX5PRKDCCA12CA1CA2
SCHEMBL15470347 0.86 ALOX5 (0.44) ALOX5PRKDCCA12CA1CA2
SCHEMBL17206598 0.84 PDE6D (0.43) PRKDCCA12CA1CA2CA9
SCHEMBL15469927 0.83 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL21915385 0.83 ALOX5 (0.37) ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed