SCHEMBL15470276

SCHEMBL15470276

c1ccc(-c2ccc3c(c2)Oc2cc(-c4ccccc4)ccc2N3c2ccc(-c3cccc4c3sc3ccccc34)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
PRKDC P78527 6/20 0.40
LIMK1 P53667 4/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
BRD4 O60885 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
KCNH2 Q12809 1/20 0.34
BRDT Q58F21 1/20 0.34
PARP14 Q460N5 1/20 0.34
ADK P55263 1/20 0.34
PDE6D O43924 1/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
F9 P00740 1/20 0.33
DNPH1 O43598 1/20 0.33
CDK8 P49336 1/20 0.31
PIM3 Q86V86 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470278 0.97 ALOX5 (0.44) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL15470280 0.94 ALOX5 (0.44) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL15470281 0.94 ALOX5 (0.41) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL13827532 0.93 ALOX5 (0.47) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL15469927 0.89 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15470274 0.88 ALOX5 (0.45) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15469877 0.87 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15470275 0.87 ALOX5 (0.48) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL15470286 0.86 ALOX5 (0.43) ALOX5PRKDCLIMK1PIK3CDPIK3CB
SCHEMBL22958742 0.86 ALOX5 (0.42) ALOX5PRKDCLIMK1PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed