SCHEMBL15470283

SCHEMBL15470283

c1ccc2c(c1)Oc1ccccc1N2c1ccc(-c2cccc3c2sc2ccccc23)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 8/20 0.41
PARP14 Q460N5 1/20 0.40
ALOX5 P09917 1/20 0.40
PIK3CD O00329 2/20 0.38
PIK3CB P42338 2/20 0.38
BRD4 O60885 1/20 0.38
PIK3CA P42336 1/20 0.38
MTOR P42345 1/20 0.38
PIK3CG P48736 1/20 0.38
KCNH2 Q12809 1/20 0.38
BRDT Q58F21 1/20 0.38
HTT P42858 1/20 0.36
PAX8 Q06710 1/20 0.36
GPR3 P46089 1/20 0.33
CCNC P24863 1/20 0.33
CDK8 P49336 1/20 0.33
ADK P55263 1/20 0.33
P2RX4 Q99571 2/20 0.32
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470286 0.86 ALOX5 (0.43) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL15470320 0.83 PARP14 (0.41) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL15470275 0.81 ALOX5 (0.48) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL15470348 0.80 PARP14 (0.41) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL15470173 0.79 GPR3 (0.37) PRKDCALOX5GPR3P2RX4POLB
SCHEMBL22432348 0.79 ALOX5 (0.35) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL22958743 0.78 ALOX5 (0.49) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL22958758 0.77 ALOX5 (0.47) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL13009203 0.77 ALOX5 (0.39) PRKDCPARP14ALOX5PIK3CDPIK3CB
SCHEMBL13827532 0.77 ALOX5 (0.47) PRKDCPARP14ALOX5PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed