Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807333 | 0.86 | KDM4E (0.56) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL1831846 | 0.80 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL14448326 | 0.80 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL15473377 | 0.78 | KDM4E (0.50) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL16437514 | 0.73 | KDM4E (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL9547184 | 0.73 | KDM4E (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL8107 | 0.73 | KDM4E (0.71) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL8763339 | 0.71 | KDM4E (0.61) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL19192288 | 0.70 | KDM4E (0.65) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL4058823 | 0.70 | KDM4E (0.58) | KDM4EMAPK1HIF1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278131-B2 | Process for lowering the viscosity of highly concentrated protein solutions | ADOCIA (FR) | 2016-03-08 | — | — | US | disclosed |
| US-9278131-B2 | Process for lowering the viscosity of highly concentrated protein solutions | ADOCIA (FR) | 2016-03-08 | — | — | US | disclosed |
| US-20140044708-A1 | Process for lowering the viscosity of highly concentrated protein solutions | ADOCIA (FR) | 2014-02-13 | — | — | US | disclosed |
| US-20140044708-A1 | Process for lowering the viscosity of highly concentrated protein solutions | ADOCIA (FR) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140044708-A1 | Process for lowering the viscosity of highly concentrated protein solutions | F13B, F5, F12 | KDM4E 2597/4885MAPK1 444/4885HIF1A 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.