Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | CBLB | Q13191 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14448326 | 0.91 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL23553592 | 0.88 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL16437514 | 0.83 | KDM4E (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL9547176 | 0.81 | DNM1 (0.38) | DNM1APAF1POLBGRK2DNMT1 | |
| SCHEMBL23691239 | 0.78 | KMT2A (0.38) | MAPK1TSHRALDH1A1DNM1APAF1 | |
| SCHEMBL14354960 | 0.77 | ADRA1A (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL1831846 | 0.77 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL15271734 | 0.75 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL15473377 | 0.75 | KDM4E (0.50) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| Acetic Acid SCHEMBL2920415 | 0.74 | DNM1 (0.46) | DNM1APAF1POLBGRK2DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | claimed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |