Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763339 | 0.85 | KDM4E (0.61) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL14448326 | 0.84 | KDM4E (0.52) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL4058823 | 0.83 | KDM4E (0.58) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL19192288 | 0.83 | KDM4E (0.65) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL15473377 | 0.82 | KDM4E (0.50) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL15470699 | 0.80 | KDM4E (0.48) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL1260787 | 0.77 | LMNA (0.40) | MAPK1TSHRALDH1A1ACHEADRA1A | |
| SCHEMBL2694530 | 0.77 | ACHE (0.37) | KDM4EMAPK1ALDH1A1ACHEADRA1A | |
| SCHEMBL16437514 | 0.77 | KDM4E (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 | |
| SCHEMBL9547184 | 0.77 | KDM4E (0.44) | KDM4EMAPK1HIF1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008044099-A1 | CHARGE TRANSFER COMPLEXES IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | GHISALBERTI CARLO (BR) | 2008-04-17 | — | — | WO | claimed |
| CN-116348084-A | Cosmetic compositions, kits, and methods of making and using the same | 莱雅公司 | 2023-06-27 | — | — | CN | disclosed |
| EP-2773633-B1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-8759349-B2 | Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| WO-2013064450-A1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |
| US-20130109697-A1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| EP-2322173-A1 | Cationic bacteriochlorophyll derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2011-05-18 | — | — | EP | disclosed |
| US-20100022483-A1 | Substituted Tetracycline Compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2010-01-28 | — | — | US | disclosed |
| WO-2008044099-A1 | CHARGE TRANSFER COMPLEXES IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASES | GHISALBERTI CARLO (BR) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109697-A1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | SCNN1B, SCNN1A, TRPM5 | KDM4E 4403/4885MAPK1 1581/4885HIF1A 1256/4885 |
| US-20100022483-A1 | Substituted Tetracycline Compounds | TET1, TET3, TLR5 | KDM4E 1796/4885MAPK1 4471/4885HIF1A 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.