Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.66 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13192838 | 0.90 | KMT2A (0.64) | KCNK3KCNK9MEN1KMT2ANPC1 | |
| SCHEMBL6014761 | 0.89 | NPC1 (0.67) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL14684329 | 0.87 | NR1H4 (0.71) | KCNK3KCNK9MEN1KMT2ANPC1 | |
| SCHEMBL18745404 | 0.87 | MEN1 (0.55) | KCNK3KCNK9MEN1KMT2ARXFP1 | |
| SCHEMBL15474235 | 0.86 | NPC1 (0.76) | KCNK3KCNK9MEN1KMT2ARXFP1 | |
| SCHEMBL13192836 | 0.85 | NPC1 (0.70) | KCNK3KCNK9MEN1KMT2ARXFP1 | |
| SCHEMBL15150112 | 0.84 | MEN1 (0.55) | KCNK3KCNK9MEN1KMT2ARXFP1 | |
| SCHEMBL8737301 | 0.84 | FFAR1 (0.69) | KCNK3KCNK9MEN1KMT2ANPC1 | |
| SCHEMBL18330540 | 0.84 | KMT2A (0.68) | KCNK3KCNK9MEN1KMT2ANPC1 | |
| SCHEMBL5168239 | 0.83 | PGR (0.72) | KCNK3MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624239-B2 | Protein kinase inhibitors | PHARMASCIENCE INC. (CA) | 2017-04-18 | — | — | US | disclosed |
| US-20140045833-A1 | Protein Kinase Inhibitors | PHARMASCIENCE INC. (CA) | 2014-02-13 | — | — | US | disclosed |
| WO-2012135944-A9 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE INC. (CA) | 2014-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045833-A1 | Protein Kinase Inhibitors | LCK, BTK, TEC | KCNK3 1767/4885KCNK9 1853/4885MEN1 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.