Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18330540 | 0.96 | KMT2A (0.68) | PGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9240473 | 0.90 | PGR (0.84) | PGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6027951 | 0.86 | MEN1 (0.88) | NPC1RAB9AMEN1KMT2AKCNK3 | |
| SCHEMBL30643220 | 0.86 | MEN1 (0.88) | NPC1RAB9AMEN1KMT2AKCNK3 | |
| SCHEMBL5694520 | 0.85 | PGR (1.00) | PGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7152809 | 0.83 | FFAR1 (0.75) | PGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30739642 | 0.83 | KMT2A (0.86) | NPC1RAB9AMEN1KMT2AKCNK3 | |
| SCHEMBL16677982 | 0.83 | PGR (0.83) | PGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8361085 | 0.83 | PGR (0.96) | PGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6479304 | 0.83 | PGR (0.72) | PGRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |