SCHEMBL15475476

SCHEMBL15475476

C=C(C(=O)OCc1ccccc1)C1CC2CCC1C2

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
EPHX2 P34913 1/20 0.39
MAPK1 P28482 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CPB1 P15086 1/20 0.39
GAA P10253 1/20 0.39
HSD11B1 P28845 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895380 0.83 HPGD (0.58) HPGDL3MBTL1ALDH1A1KDM4EHTT
SCHEMBL8553213 0.79 ALDH1A1 (0.49) L3MBTL1ALDH1A1MAPK1SLC6A2SLC6A3
SCHEMBL30258886 0.76 HPGD (0.49) HPGDL3MBTL1ALDH1A1NPC1RAB9A
SCHEMBL15475334 0.73 ALDH1A1 (0.43) HPGDALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL2352806 0.73 ALDH1A1 (0.51) L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL21895656 0.73 HPGD (0.56) HPGDL3MBTL1ALDH1A1KDM4EHTT
SCHEMBL13638725 0.73 CPB1 (0.57) HPGDALDH1A1SMN1; SMN2EPHX2CPB1
SCHEMBL6809188 0.73 CPB1 (0.57) HPGDALDH1A1SMN1; SMN2EPHX2CPB1
SCHEMBL6813787 0.73 CPB1 (0.57) HPGDALDH1A1SMN1; SMN2EPHX2CPB1
SCHEMBL13688353 0.72 TSHR (0.45) L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140049728-A1 LIGHT GUIDE PLATE, LIGHT-EMITTING UNIT AND LIQUID CRYSTAL DISPLAY DEVICE HAVING THE SAME CHI MEI CORPORATION (TW) 2014-02-20 US disclosed