Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15475791 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1HPGDACHETDP1 | |
| SCHEMBL15171934 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1HPGDACHETDP1 | |
| SCHEMBL15171925 | 0.94 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2HCAR2 | |
| SCHEMBL15154611 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL15154487 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL15154397 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL15174198 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL15475479 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL15154156 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1MEN1 | |
| SCHEMBL15154344 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1HPGDTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140051705-A1 | Morpholinoalkyl Fumarate Compounds, Pharmaceutical Compositions, and Methods of Use | XENOPORT, INC. (US) | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051705-A1 | Morpholinoalkyl Fumarate Compounds, Pharmaceutical Compositions, and Methods of Use | FH, APC, HTT | KDM4E 3249/4885ALDH1A1 2754/4885HPGD 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.