Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 14/20 | 0.95 |
| ▸ | GLRB | P48167 | 14/20 | 0.95 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.95 |
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.95 |
| ▸ | MEN1 | O00255 | 2/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.95 |
| ▸ | SCN1A | P35498 | 1/20 | 0.95 |
| ▸ | TAS2R46 | P59540 | 1/20 | 0.95 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.95 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.95 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Strychnine SCHEMBL21985190 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL14047653 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL29352583 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL29362678 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL12549549 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL14117483 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL14029424 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL93798 | 0.97 | GLRA1 (1.00) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL25300604 | 0.96 | GLRA1 (0.98) | GLRA1GLRBCYP3A4TAS2R10MEN1 | |
| Strychnine SCHEMBL31047368 | 0.96 | GLRA1 (0.98) | GLRA1GLRBCYP3A4TAS2R10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180042899-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-15 | — | — | US | disclosed |
| US-20140050694-A1 | Method of Treating Transplant Rejection and Autoimmune Diseases | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-20 | — | — | US | disclosed |