SCHEMBL15475846

SCHEMBL15475846

C[CH]Oc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
FABP3 P05413 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
HTR2A P28223 4/20 0.32
HTR2C P28335 4/20 0.32
HTR2B P41595 2/20 0.32
AHR P35869 2/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547749 0.80 ALDH1A1 (0.40) CYP3A4MRGPRX4TDP1
SCHEMBL2089458 0.77 CYP3A4 (0.36) CYP3A4MAPK1FABP3MRGPRX4GPR84
SCHEMBL9486392 0.77 HTR2A (0.33) CYP3A4MAPK1MRGPRX4GPR84HTR2A
SCHEMBL9243827 0.74 MRGPRX4 (0.31) CYP3A4MAPK1MRGPRX4GPR84HTR2A
SCHEMBL53547 0.73 ALDH1A1 (0.46) CYP3A4MAPK1HTR2AHTR2CHTR2B
SCHEMBL30715275 0.73 ALDH1A1 (0.46) CYP3A4MAPK1HTR2AHTR2CHTR2B
SCHEMBL9067780 0.72 CYP1A2 (0.52) MAPK1GPR84TDP1
SCHEMBL11283671 0.72 CYP3A4 (0.43) CYP3A4MAPK1FABP3MRGPRX4GPR84
SCHEMBL1547763 0.71 TTR (0.47) TDP1
SCHEMBL1547838 0.71 TP53 (0.42) CYP3A4HTR2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8980506-B2 Photosensitive resin composition and application thereof CHI MEI CORPORATION (TW) 2015-03-17 US disclosed
US-20140051017-A1 PHOTOSENSITIVE RESIN COMPOSITION AND APPLICATION THEREOF CHI MEI CORPORATION (TW) 2014-02-20 US disclosed