Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ESRRA | P11474 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099452 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2A6TSHRNPC1RAB9A | |
| SCHEMBL9066754 | 0.76 | PKM (0.49) | LMNAKDM4EGPR84ALDH1A1KMT2A | |
| SCHEMBL535467 | 0.74 | LMNA (0.42) | TSHRNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL13019803 | 0.73 | CYP1A2 (0.54) | CYP1A2CYP2A6TSHRNPC1RAB9A | |
| SCHEMBL9188264 | 0.72 | CYP1A2 (0.59) | CYP1A2CYP2A6TSHRNPC1RAB9A | |
| SCHEMBL3751527 | 0.72 | CYP1A2 (0.59) | CYP1A2CYP2A6TSHRNPC1RAB9A | |
| SCHEMBL15475846 | 0.72 | CYP3A4 (0.36) | GPR84TDP1MAPK1 | |
| SCHEMBL2473555 | 0.72 | CYP2A6 (1.00) | CYP1A2CYP2A6TSHRNPC1RAB9A | |
| SCHEMBL29494605 | 0.72 | CYP2A6 (1.00) | CYP1A2CYP2A6TSHRNPC1RAB9A | |
| SCHEMBL9067781 | 0.72 | KDM4E (0.56) | CYP1A2CYP2A6TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5183870-A | A curable polybutylene glycol di(meth)acrylate, a urethane or epoxy (meth)acrylate and a (meth)acrylate; heat and water resistance; impact strength; dyeability; workability | MITSUBISHI RAYON CO., LTD (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0441383-A2 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |