SCHEMBL15480238

SCHEMBL15480238

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc5ccccc5c4)ccc2n3-c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-3)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ ATM Q13315 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ TSPO P30536 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15480232 0.98 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL16596659 0.95 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL13566756 0.94 KDM4E (0.35) KDM4EATML3MBTL1TSPO
SCHEMBL13444270 0.94 KDM4E (0.35) KDM4EATML3MBTL1TSPO
SCHEMBL24569001 0.94 KDM4E (0.36) PDK2KDM4EATML3MBTL1TSPO
SCHEMBL19652820 0.93 KDM4E (0.33) KDM4EATML3MBTL1TSPO
SCHEMBL19652819 0.93 KDM4E (0.33) KDM4EATML3MBTL1TSPO
SCHEMBL19653724 0.93 KDM4E (0.33) KDM4EATML3MBTL1TSPO
SCHEMBL19653723 0.93 KDM4E (0.33) KDM4EATML3MBTL1TSPO
SCHEMBL24667875 0.92 KDM4E (0.36) PDK2KDM4EATML3MBTL1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49237-E1 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2022-10-04 — — US disclosed
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 — — US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 — — US disclosed
US-20160268517-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-09-15 — — US disclosed
US-20160268517-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-09-15 — — US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 — — US disclosed
US-9397307-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2016-07-19 — — US disclosed
US-20150249219-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 — — US disclosed
US-20150249219-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-09-03 — — US disclosed
US-20140306207-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-16 — — US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 — — US disclosed
US-20140231769-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-08-21 — — US disclosed
US-20140048784-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-02-20 — — US disclosed
US-20140048784-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 PDK2 599/4885KDM4E 3248/4885ATM 2324/4885
US-20160268517-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME L1CAM, CCNT1, CCNA1 PDK2 1611/4885KDM4E 2191/4885ATM 4082/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 PDK2 599/4885KDM4E 3248/4885ATM 2324/4885
US-20150249219-A1 BISCARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME L1CAM, CCNT1, CCNA1 PDK2 1635/4885KDM4E 2205/4885ATM 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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