Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.84 |
| ▸ | NAAA | Q02083 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MLYCD | O95822 | 1/20 | 0.64 |
| ▸ | THRA | P10827 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428355 | 0.92 | MAPK1 (1.00) | MAPK1NAAAL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL25374405 | 0.91 | MAPK1 (0.69) | MAPK1NAAAL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL28737143 | 0.91 | MAPK1 (0.69) | MAPK1NAAAL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL30527282 | 0.90 | L3MBTL1 (0.86) | MAPK1NAAAL3MBTL1MLYCDTHRA | |
| SCHEMBL845966 | 0.90 | L3MBTL1 (0.86) | MAPK1NAAAL3MBTL1MLYCDTHRA | |
| SCHEMBL10481026 | 0.90 | L3MBTL1 (0.86) | MAPK1NAAAL3MBTL1MLYCDTHRA | |
| SCHEMBL6535660 | 0.90 | L3MBTL1 (0.86) | MAPK1NAAAL3MBTL1MLYCDTHRA | |
| SCHEMBL9504178 | 0.90 | L3MBTL1 (0.86) | MAPK1NAAAL3MBTL1MLYCDTHRA | |
| SCHEMBL9265536 | 0.90 | L3MBTL1 (0.86) | MAPK1NAAAL3MBTL1MLYCDTHRA | |
| SCHEMBL258708 | 0.90 | L3MBTL1 (0.86) | MAPK1NAAAL3MBTL1MLYCDTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170020874-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENT AB (SE) | 2017-01-26 | — | — | US | disclosed |
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENTIFIC AB | 2014-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051716-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | MAPK1 2601/4885NAAA 400/4885L3MBTL1 1891/4885 |
| US-20170020874-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC2 | MAPK1 2601/4885NAAA 400/4885L3MBTL1 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.