SCHEMBL15480787

SCHEMBL15480787

Cc1ccc(Nc2ccc3c(c2)c2ccccc2n3-c2ccc(C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HPGD P15428 1/20 0.46
ATM Q13315 1/20 0.46
MAPT P10636 8/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
LMNA P02545 4/20 0.43
HTT P42858 2/20 0.40
KDM1A O60341 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
APP P05067 1/20 0.39
NPY5R Q15761 1/20 0.38
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
CDC25B P30305 1/20 0.38
UBE2I P63279 1/20 0.38
SAE1 Q9UBE0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12722061 0.95 L3MBTL1 (0.53) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL20083339 0.92 KDM4E (0.47) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL23620635 0.92 L3MBTL1 (0.53) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL13969315 0.89 KDM4E (0.60) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL13291295 0.88 HPGD (0.39) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL10109752 0.88 HPGD (0.48) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL14902282 0.88 HPGD (0.44) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL14029467 0.88 HPGD (0.47) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL29981971 0.87 KDM4E (0.62) KDM4EL3MBTL1HPGDATMMAPT
SCHEMBL18055091 0.87 KDM4E (0.62) KDM4EL3MBTL1HPGDATMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014027822-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-02-20 WO disclosed