Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549196 | 1.00 | ALDH1A1 (0.51) | ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1549223 | 1.00 | ALDH1A1 (0.51) | ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1549160 | 0.92 | LMNA (0.54) | ALDH1A1TP53POLBADRB2ADRB1 | |
| SCHEMBL1548630 | 0.92 | LMNA (0.54) | ALDH1A1TP53POLBADRB2ADRB1 | |
| SCHEMBL1548628 | 0.92 | LMNA (0.54) | ALDH1A1TP53POLBADRB2ADRB1 | |
| SCHEMBL1549195 | 0.91 | KMT2A (0.48) | ALDH1A1TSHRSMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL1548828 | 0.91 | GAA (0.53) | ALDH1A1TP53CTSDSMN1; SMN2 | |
| SCHEMBL1548415 | 0.91 | GAA (0.53) | ALDH1A1TP53CTSDSMN1; SMN2 | |
| SCHEMBL1548413 | 0.91 | GAA (0.53) | ALDH1A1TP53CTSDSMN1; SMN2 | |
| SCHEMBL1548595 | 0.91 | KMT2A (0.48) | ALDH1A1TSHRSMN1; SMN2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444196-B1 | ALPHA-OXYGENATED CARBOXYLIC ACID PHENETHYLAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-18 | — | — | EP | claimed |
| US-7601674-B2 | for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | claimed |
| US-20050020450-A1 | for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. | 2005-01-27 | — | — | US | claimed |
| EP-1444196-A1 | NOVEL ALPHA-OXYGENATED OR ALPHA-THIOLATED CARBOXYLIC ACID PENETHYLAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2004-08-11 | — | — | EP | claimed |
| WO-2003042167-A1 | NOVEL α-OXYGENATED OR α-THIOLATED CARBOXYLIC ACID PENETHYLAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | claimed |
| EP-1444196-B1 | ALPHA-OXYGENATED CARBOXYLIC ACID PHENETHYLAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| EP-1444196-B1 | ALPHA-OXYGENATED CARBOXYLIC ACID PHENETHYLAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| EP-2314568-A2 | Novel alpha-oxygenated or alpha-thiolated carboxylic acid phenethylamide derivatives | Syngenta Participations AG (CH) | 2011-04-27 | — | — | EP | disclosed |
| EP-2314568-A2 | Novel alpha-oxygenated or alpha-thiolated carboxylic acid phenethylamide derivatives | Syngenta Participations AG (CH) | 2011-04-27 | — | — | EP | disclosed |
| US-7601674-B2 | for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601674-B2 | for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601674-B2 | for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20050020450-A1 | for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. | 2005-01-27 | — | — | US | disclosed |
| EP-1444196-A1 | NOVEL ALPHA-OXYGENATED OR ALPHA-THIOLATED CARBOXYLIC ACID PENETHYLAMIDE DERIVATIVES | Syngenta Participations AG (CH) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003042167-A1 | NOVEL α-OXYGENATED OR α-THIOLATED CARBOXYLIC ACID PENETHYLAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020450-A1 | for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | CBR3, CBR1, MSR1 | ALDH1A1 2297/4885PLAAT3 2837/4885PLAAT5 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.