Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GZMB | P10144 | 15/20 | 0.67 |
| ▸ | ACE | P12821 | 5/20 | 0.65 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.65 |
| ▸ | MME | P08473 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489425 | 0.90 | GZMB (0.64) | GZMBACEACE2 | |
| SCHEMBL15489384 | 0.88 | GZMB (0.78) | GZMBACEACE2 | |
| SCHEMBL15489426 | 0.88 | GZMB (0.66) | GZMBACEACE2 | |
| SCHEMBL15489441 | 0.88 | GZMB (0.63) | GZMBACEACE2 | |
| SCHEMBL15489382 | 0.86 | GZMB (0.65) | GZMBACEACE2 | |
| SCHEMBL15489530 | 0.86 | GZMB (0.66) | GZMB | |
| SCHEMBL15489474 | 0.86 | GZMB (0.64) | GZMBACEACE2 | |
| SCHEMBL15489476 | 0.86 | GZMB (0.62) | GZMBACEACE2 | |
| SCHEMBL15489437 | 0.86 | GZMB (0.62) | GZMBACEACE2 | |
| SCHEMBL15489477 | 0.86 | GZMB (0.62) | GZMBACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140056964-A1 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140056964-A1 | GRANZYME B INHIBITOR COMPOSITIONS, METHODS AND USES FOR PROMOTING WOUND HEALING | GZMB, PRF1, SERPINB1 | GZMB 1/4885ACE 2391/4885ACE2 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.