Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL27130007 | 0.97 | CA4 (0.38) | CA4CA1FFAR3HDAC3HDAC1 | |
| Methacrylic Acid SCHEMBL27040264 | 0.95 | CA4 (0.36) | CA4CA1FFAR3HDAC3HDAC1 | |
| SCHEMBL28120141 | 0.87 | CA1 (0.37) | CA4CA1FFAR3HDAC3HDAC1 | |
| Methacrylic Acid SCHEMBL28074050 | 0.87 | CA4 (0.47) | CA4CA1TDP1FAHD1TSHR | |
| Methacrylic Acid SCHEMBL28066009 | 0.87 | CA4 (0.35) | CA4CA1FFAR3HDAC3HDAC1 | |
| Methacrylic Acid SCHEMBL154988 | 0.85 | CA4 (0.41) | CA4CA1FFAR3HDAC3HDAC1 | |
| Methacrylic Acid SCHEMBL29008976 | 0.84 | FFAR3 (0.32) | CA4FFAR3HDAC3HDAC1HDAC2 | |
| Acetic Acid SCHEMBL8458828 | 0.84 | CA1 (0.56) | CA4CA1FFAR3HDAC3HDAC1 | |
| Methacrylic Acid SCHEMBL2139811 | 0.82 | CA4 (0.38) | CA4CA1FFAR3HDAC3HDAC1 | |
| Acetic Acid SCHEMBL8723844 | 0.81 | CA1 (0.53) | CA4CA1FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118763177-A | Sodium supplement additive and application thereof in sodium ion battery | 浙江华宇钠电新能源科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-118406179-A | Free emulsifier-free dispersing agent-free polymer microsphere and preparation method and application thereof | 东南大学 | 2024-07-30 | — | — | CN | claimed |
| CN-115850570-B | Hyperbranched polymer microsphere filtrate reducer and preparation method and application thereof | 长江大学 | 2023-11-28 | — | — | CN | claimed |
| CN-115894817-A | Vinyl polyether modified structure polycarboxylate superplasticizer and preparation method thereof | 科之杰新材料集团有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115819685-A | Side chain end-capped polycarboxylate superplasticizer and preparation method thereof | 科之杰新材料集团有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-114395378-B | Synthesis of high-temperature-resistant modified nano-alumina plugging agent and oil-based drilling fluid | 西南石油大学 | 2023-01-31 | — | — | CN | claimed |
| CN-115594792-A | Phosphorus-sulfur synergistic flame-retardant composition, and preparation method and application thereof | 宁波谱多琟克科技发展有限责任公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115160903-A | Amphiphilic marine antifouling paint cured by ultraviolet light | 常熟理工学院 | 2022-10-11 | — | — | CN | claimed |
| CN-114395378-A | Synthesis of high-temperature-resistant modified nano-alumina plugging agent and oil-based drilling fluid | 西南石油大学 | 2022-04-26 | — | — | CN | claimed |
| CN-115135677-B | Compounds and polymer compositions containing the same | 三菱化学株式会社 | 2025-04-29 | — | — | CN | disclosed |
| CN-118663082-B | Multilayer composite bionic structure oxygenation membrane and preparation method and application thereof | 天津大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-118359953-B | Photo-curing coating, optical film and application thereof | 宁波天璇新材料科技有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119331160-A | Reactive acrylate dispersing agent and preparation method and application thereof | 宁波天璇新材料科技有限公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-118763177-B | Sodium supplement additive and application thereof in sodium ion battery | 浙江华宇钠电新能源科技有限公司 | 2025-01-10 | — | — | CN | disclosed |
| US-20120057269-A1 | CONDUCTIVE COMPOSITION AND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2012-03-08 | — | — | US | disclosed |
| US-8097184-B2 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20100097743-A1 | CONDUCTIVE COMPOSITION VAND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-20100098841-A1 | CONDUCTIVE COMPOSITION VAND CONDUCTIVE CROSS-LINKED PRODUCT, CAPACITOR AND PRODUCTION METHOD THEREOF, AND ANTISTATIC COATING MATERIAL, ANTISTATIC COATING, ANTISTATIC FILM, OPTICAL FILTER, AND OPTICAL INFORMATION RECORDING MEDIUM | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-04-22 | — | — | US | disclosed |
| US-7666326-B2 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20060047030-A1 | Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium | SHIN-ETSU POLYMER CO., LTD | 2006-03-02 | — | — | US | disclosed |